{"id":3377,"date":"2026-05-07T14:02:30","date_gmt":"2026-05-07T12:02:30","guid":{"rendered":"https:\/\/genocan.eu\/?p=3377"},"modified":"2026-05-28T09:51:47","modified_gmt":"2026-05-28T07:51:47","slug":"a-new-era-in-cane-corso-genetic-testing-health-colour-and-longevity-in-one-package","status":"publish","type":"post","link":"https:\/\/genocan.eu\/cs\/news\/a-new-era-in-cane-corso-genetic-testing-health-colour-and-longevity-in-one-package\/","title":{"rendered":"Nov\u00e1 \u00e9ra genetick\u00e9ho testov\u00e1n\u00ed u Cane Corso: zdrav\u00ed, zbarven\u00ed a dlouhov\u011bkost v jednom bal\u00ed\u010dku"},"content":{"rendered":"

GenoCan p\u0159edstavuje nov\u00fd komplexn\u00ed bal\u00ed\u010dek genetick\u00fdch test\u016f vytvo\u0159en\u00fd speci\u00e1ln\u011b pro plemeno Cane Corso. Nejde pouze o b\u011b\u017en\u00fd DNA test \u2014 tento panel spojuje d\u016fle\u017eit\u00e9 informace o d\u011bdi\u010dn\u00fdch onemocn\u011bn\u00edch, genetick\u00fdch predispozic\u00edch ke zbarven\u00ed srsti a unik\u00e1tn\u00ed \u010d\u00e1st zam\u011b\u0159enou na dlouhov\u011bkost.<\/a><\/p>\n\n\n\n

Pro chovatele Cane Corso je tento panel velmi u\u017eite\u010dn\u00fdm n\u00e1strojem. Pom\u00e1h\u00e1 p\u0159i zodpov\u011bdn\u00e9m pl\u00e1nov\u00e1n\u00ed kryt\u00ed, v\u00fdb\u011bru vhodn\u00fdch chovn\u00fdch spojen\u00ed i ur\u010den\u00ed predispozic pro dlouhov\u011bkost.<\/p>\n\n\n\n

1. D\u011bdi\u010dn\u00e1 onemocn\u011bn\u00ed<\/h2>\n\n\n\n

Panel zahrnuje n\u011bkolik monogenn\u00edch onemocn\u011bn\u00ed, kter\u00e1 jsou relevantn\u00ed pro Cane Corso a p\u0159\u00edbuzn\u00e1 molossoidn\u00ed plemena:<\/p>\n\n\n\n

Dental-Skeletal-Retinal Anomaly \u2014 DSRA<\/strong>
Specifick\u00e9 d\u011bdi\u010dn\u00e9 onemocn\u011bn\u00ed plemene Cane Corso postihuj\u00edc\u00ed zuby, kostru a o\u010di.<\/p>\n\n\n\n

Canine Multifocal Retinopathy type 1 \u2014 CMR1<\/strong>
D\u011bdi\u010dn\u00e9 o\u010dn\u00ed onemocn\u011bn\u00ed, kter\u00e9 m\u016f\u017ee zp\u016fsobovat zm\u011bny na s\u00edtnici.<\/p>\n\n\n\n

Degenerativn\u00ed myelopatie \u2014 DM<\/strong>
Neurologick\u00e9 onemocn\u011bn\u00ed, kter\u00e9 se obvykle objevuje u star\u0161\u00edch ps\u016f a zp\u016fsobuje postupn\u00e9 sl\u00e1bnut\u00ed zadn\u00edch kon\u010detin.<\/p>\n\n\n\n

Hyperurikosurie \u2014 HUU<\/strong>
Metabolick\u00e1 porucha spojen\u00e1 se zv\u00fd\u0161en\u00fdm vylu\u010dov\u00e1n\u00edm kyseliny mo\u010dov\u00e9 mo\u010d\u00ed a vy\u0161\u0161\u00edm rizikem tvorby mo\u010dov\u00fdch kamen\u016f.<\/p>\n\n\n\n

Neuron\u00e1ln\u00ed ceroidn\u00ed lipofuscin\u00f3za typ 1 \u2014 NCL1<\/strong>
Velmi vz\u00e1cn\u00e9 neurodegenerativn\u00ed onemocn\u011bn\u00ed, kter\u00e9 je v panelu za\u0159azeno pro komplexn\u011bj\u0161\u00ed genetick\u00fd screening.<\/p>\n\n\n\n

2. Predispozice ke zbarven\u00ed srsti<\/h2>\n\n\n\n

Sou\u010d\u00e1st\u00ed panelu je tak\u00e9 testov\u00e1n\u00ed d\u016fle\u017eit\u00fdch gen\u016f ovliv\u0148uj\u00edc\u00edch zbarven\u00ed srsti u Cane Corso. V\u00fdsledky pom\u00e1haj\u00ed l\u00e9pe posoudit genetick\u00e9 predispozice pro barvy a vzory, jako je \u010dern\u00e1, \u0161ed\u00e1\/modr\u00e1, plav\u00e1, formentino, hn\u011bd\u00e1 nebo \u017e\u00edhan\u00e1.<\/p>\n\n\n\n

Testovan\u00e9 barevn\u00e9 lokusy zahrnuj\u00ed:<\/p>\n\n\n\n

E-lokus \u2014 MC1R<\/strong>
Melanistick\u00e1 maska a recesivn\u00ed \u010derven\u00e1\/\u017elut\u00e1 barva.<\/p>\n\n\n\n

K-lokus \u2014 CBD103<\/strong>
Dominantn\u00ed \u010dern\u00e1 barva a d\u011bdi\u010dnost souvisej\u00edc\u00ed se \u017e\u00edh\u00e1n\u00edm.<\/p>\n\n\n\n

A-lokus \u2014 ASIP<\/strong>
Plav\u00e9\/sable zbarven\u00ed, tan-point a dal\u0161\u00ed aguti vzory.<\/p>\n\n\n\n

D-lokus \u2014 MLPH<\/strong>
\u0158ed\u011bn\u00ed barvy, kter\u00e9 je zodpov\u011bdn\u00e9 za \u0161ed\u00e9\/modr\u00e9 a formentino odst\u00edny.<\/p>\n\n\n\n

B-lokus \u2014 TYRP1<\/strong>
Varianty souvisej\u00edc\u00ed s hn\u011bd\u00fdm\/\u010dokol\u00e1dov\u00fdm pigmentem.<\/p>\n\n\n\n

U \u017e\u00edh\u00e1n\u00ed je pot\u0159eba v\u00fdsledek v\u017edy posuzovat spole\u010dn\u011b s viditeln\u00fdm zbarven\u00edm psa, barvou obou rodi\u010d\u016f a barvami, kter\u00e9 se v dan\u00e9 linii vyskytuj\u00ed. \u017d\u00edh\u00e1n\u00ed nelze v\u017edy stoprocentn\u011b p\u0159edpov\u011bd\u011bt pouze z DNA v\u00fdsledku.<\/p>\n\n\n\n

3. Dlouhov\u011bkost<\/h2>\n\n\n\n

Jednou z nejzaj\u00edmav\u011bj\u0161\u00edch \u010d\u00e1st\u00ed panelu je sekce zam\u011b\u0159en\u00e1 na dlouhov\u011bkost. Byla vyvinuta ve spolupr\u00e1ci s Dr. Korcem<\/strong> na z\u00e1klad\u011b v\u011bdeck\u00e9 publikace<\/strong> Four novel genes associated with longevity found in Cane Corso purebred dogs<\/em>, ve kter\u00e9 byl v\u00fdzkum proveden p\u0159\u00edmo u ps\u016f plemene Cane Corso.<\/p>\n\n\n\n

Pr\u00e1v\u011b to d\u011bl\u00e1 tuto \u010d\u00e1st panelu pro plemeno Cane Corso mimo\u0159\u00e1dn\u011b zaj\u00edmavou. Panel hodnot\u00ed vybran\u00e9 genetick\u00e9 markery spojovan\u00e9 s del\u0161\u00ed d\u00e9lkou \u017eivota v okol\u00ed gen\u016f TDRP, MC2R, FBXL21 a FBXO25. V\u00fdsledek ukazuje, zda m\u00e1 dan\u00fd pes genetick\u00e9 predispozice pro dlouhov\u011bkost.<\/p>\n\n\n\n

D\u00e9lku \u017eivota samoz\u0159ejm\u011b ovliv\u0148uje mnoho faktor\u016f, nap\u0159\u00edklad zdravotn\u00ed p\u00e9\u010de, v\u00fd\u017eiva, t\u011blesn\u00e1 kondice nebo \u017eivotn\u00ed styl. Tato sekce v\u0161ak p\u0159in\u00e1\u0161\u00ed chovatel\u016fm dal\u0161\u00ed cennou informaci, kterou mohou zohlednit p\u0159i dlouhodob\u00e9m pl\u00e1nov\u00e1n\u00ed chovu.<\/p>\n\n\n\n

Pro\u010d testovat Cane Corso t\u00edmto panelem?<\/h2>\n\n\n\n

Nov\u00fd Pr\u00e9miov\u00fd genetick\u00fd bal\u00ed\u010dek pro Cane Corso<\/a> p\u0159edstavuje v\u00fdznamn\u00fd posun v genetick\u00e9m testov\u00e1n\u00ed tohoto plemene. V jednom testu spojuje screening d\u011bdi\u010dn\u00fdch onemocn\u011bn\u00ed, genetiku zbarven\u00ed srsti a unik\u00e1tn\u00ed markery spojovan\u00e9 s dlouhov\u011bkost\u00ed.<\/p>\n\n\n\n

Chcete m\u00edt p\u0159ehled o novink\u00e1ch u Cane Corso? P\u0159idejte se k n\u00e1m na Facebooku<\/a>.<\/p>\n\n\n\n

Reference:<\/strong> Korec et al. Four novel genes associated with longevity found in Cane Corso purebred dogs. BMC Vet Res. 2022 May 19;18(1):188.<\/em><\/p>","protected":false},"excerpt":{"rendered":"

GenoCan p\u0159edstavuje nov\u00fd komplexn\u00ed bal\u00ed\u010dek genetick\u00fdch test\u016f vytvo\u0159en\u00fd speci\u00e1ln\u011b pro plemeno Cane Corso. Nejde pouze o b\u011b\u017en\u00fd DNA test \u2014 tento panel spojuje d\u016fle\u017eit\u00e9 informace o d\u011bdi\u010dn\u00fdch onemocn\u011bn\u00edch, genetick\u00fdch predispozic\u00edch ke zbarven\u00ed srsti a unik\u00e1tn\u00ed \u010d\u00e1st zam\u011b\u0159enou na dlouhov\u011bkost. Pro chovatele Cane Corso je tento panel velmi u\u017eite\u010dn\u00fdm n\u00e1strojem. Pom\u00e1h\u00e1 p\u0159i zodpov\u011bdn\u00e9m pl\u00e1nov\u00e1n\u00ed kryt\u00ed, v\u00fdb\u011bru […]<\/p>\n","protected":false},"author":2,"featured_media":3407,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[17],"tags":[],"class_list":["post-3377","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t