Dental-skeletal-retinal anomaly

Dental skeletal retinal anomaly (DSRA) is an inherited genetic syndrome that affects dogs of the Cane Corso breed. The disease is clinically characterized by skeletal abnormalities, progressive retinal involvement leading to loss of vision, and dental imperfections (brittle, discoloured, translucent teeth). DSRA is inherited in an autosomal recessive manner, and the affected puppy is the offspring of a sire and a dam who are both carriers of the disease.