The ridge formation in Rhodesian and Thai Ridgeback is caused by mutation (duplication of stretch of DNA sequence including several genes). The mutation is called simply a ridge gene and shows dominant inheritance.
The disease is characterized by myoclonic seizures, which cause rapid uncontrolled muscle jerks and twitches
It is a congenital disorder of skeletal muscle which is manifested by the significant increase in temperature (hyperthermia) up to 45°C, accelerated and irregular heart rate (tachycardia and arrhythmia), hyperventilation, muscle rigidity and may result in renal failure and death.
The tested variant causes coat colour dilution. In black-coloured individuals of different breeds, the hair appears gray (blue). In Rhodesian Ridgebacks, dilution is manifested by cream-coloured hair compared to traditional red wheaten. The inheritance is autosomal recessive.
The tested variant causes brown colouring of a nose ("livernose"), mucous membranes and claws. The inheritance is autosomal recessive (black allele and colour is dominant).
It is a neuromuscular disease causing a gradual muscle weakness on the hindlimb and back, which is manifested by poor coordination of movements, cramped and asymmetric walking, or incontinence.
It is a rare blood disorder in which the blood is unable to clot properly, leading to excessive bleeding. Bleeding can be initiated from injury, trauma and surgery.
Chondrodysplasia (CDPA) is a genetic disease causing abnormal growth of cartilage and early changes in the structure of growth plates. The affected dogs are generally characterized by a normal sized trunk and short limbs.
Pituitary dwarfism (also called nanism) is a disease that leads to a dwarf growth of dogs and is caused by degeneration of the pituitary gland with a consequent lack of production of growth hormones