Malignant Hyperthermia

Canine stress syndrome


It is a congenital disorder of skeletal muscle which is manifested by the significant increase in temperature (hyperthermia) up to 45°C, accelerated and irregular heart rate (tachycardia and arrhythmia), hyperventilation, muscle rigidity and may result in renal failure and death.

In genetically susceptible individuals, a particular group of volatile anesthetics may trigger the symptome. The inheritance of the disease is autosomal dominant.

For breeds

American Cocker Spaniel, Australian Shepherd, Boston Terrier, Cane Corso, Coton de Tulear, Czechoslovakian Wolfdog, French Bulldog, German Shepherd, Irish Setter, Nova Scotia Duck Tolling Retriever, Poodle Miniature, Poodle Standard, Poodle Toy, Rhodesian Ridgeback, Saarloos Wolfdog, Siberian Husky, Staffordshire Bull Terriers, Thai Ridgeback, Welsh Corgi Cardigan, Welsh Corgi Pembroke, ...other breeds,

Gene and mutation

RYR1, c.1640T>C

49 €

49 €