RIDGE, JME, DM, MH, DLOK, BLOK, HEMB, EOAD
Complete package of genetic tests for prevention of genetic health in Rhodesian Ridgebacks.
The package includes genetic tests:
- Predisposition for Ridge (RIDGE)
- Juvenile Myoclonic Epilepsy (JME)
- Malignant Hyperthermia (MH)
- Degenerative Myelopathy (DM)
- D-Locus (DLOK)
- B-Locus (BLOK)
- Hemophilia B (HEMB)
- Early Onset Hearing Loss (EOAD)
Please note that results will be available within 2-3 weeks after delivery of the sample to the laboratory.
Gene and tested mutations/variants
RIDGE:133 kb duplication of several genes (FGF3, FGF4, FGF19 a ORAOV1); JME:DIRAS1, c.564_567delAGAC; MH:RYR1, c.1640T>C; DM:SOD1, exon 2; DLOK:MLPH, c.-22G>A; BLOK:TYRP1, (bs - c.991C>T; bc - c.121T>A; bd - c.1033_1035del); HEMB:F9, c.731G>A; EOAD:EPS8L2, chr18:g.25868739-25868751del