Ridge gene test, Ridgelessness, Dermoid Sinus predisposition
RIDGE
The ridge formation in Rhodesian and Thai Ridgeback is caused by mutation (duplication of stretch of DNA sequence including several genes). The mutation is called simply a ridge gene and shows dominant inheritance.
We have developed the genetic test, which distinguishes dominant homozygotes (R/R – two ridge genes) from heterozygotes (R/r – one ridge gene). Using our genetic test, a breeder may predict birth of ridgeless puppies (see Table below, example for Rhodesian ridgeback).
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Ridge predisposition in Rhodesian Ridgebacks* |
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Parents (Sire x Dam) |
Puppies |
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ridged |
ridgeless |
risk of Dermoid sinus |
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R/R x R/R |
100% |
0% |
increased |
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R/R x R/r nebo R/r x R/R |
>95% |
<5% |
normal |
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R/r x R/r |
75% |
25% |
normal / low |
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R/R – dominant homozygote (2 ridge genes), R/R puppy is always ridged R/r – heterozygote (1 ridge gene), R/r puppy is in 95% ridged, in approx. 5% ridgeless (ridge gene is suppressed) *prediction based on research, updated 1.2.2017 |
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For breeds
Rhodesian Ridgeback, Thai Ridgeback,
Gene and mutation
133 kb duplication of several genes (FGF3, FGF4, FGF19 a ORAOV1)
76 €
