Ridge predisposition

The ridge formation in Rhodesian and Thai Ridgeback is caused by mutation (duplication of stretch of DNA sequence including several genes). The mutation is called simply a ridge gene and shows dominant inheritance.

We have developed the genetic test, which distinguishes dominant homozygotes (R/R – two ridge genes) from heterozygotes (R/r – one ridge gene). Using our genetic test, a breeder may predict birth of ridgeless puppies (see Table below, example for Rhodesian ridgeback).

Ridge predisposition in Rhodesian Ridgebacks*

Parents (Sire x Dam)

Puppies

ridged

ridgeless

risk of Dermoid sinus

R/R x R/R

100%

0%

increased

R/R x R/r nebo R/r x R/R

>95%

<5%

normal

R/r x R/r

75%

25%

normal / low

R/R – dominant homozygote (2 ridge genes), R/R puppy is always ridged

R/r – heterozygote (1 ridge gene), R/r puppy is in 95% ridged, in approx. 5% ridgeless (ridge gene is suppressed)

*prediction based on research, updated 1.2.2017

For breeds

Rhodesian Ridgeback, Thai Ridgeback,

Gene and mutation

133 kb duplikace zahrnující geny (FGF3, FGF4, FGF19 a ORAOV1)

77 €

77 €